Healthy Volunteer Protocol
Healthy Volunteer Protocol - MEG component
This large scale study is being conducted to collect MEG on a large number of healthy controls with matched MRI/fMRI data The study is described in full detail in the manuscript: __Enter Link Here__
Datasets
- Somatosensory
- Sternberg working memory
- Hariri hammer
- Movie - "Growth" (Groei) https://www.imdb.com/title/tt6386160/
- Resting State - Eyes closed
- Auditory Oddball
- Go/No-go
BIDS format / OpenNeuro
All data is be converted to BIDS format and uploaded to OpenNeuro as an open access dataset. Data triggers are cleaned using several routines listed below. These have been used to realign stimulus triggers to optical onset of the projector. Datasets that have logfiles have been merged with the trigger data to label triggers and responses.
More details can be seen at: https://megcore.nih.gov/index.php/Healthy_Volunteer_Protocol_Upload_Process
Code
pyctf - core interface to CTF processing in python. Includes general bids related functions as well as general purpose MEG processing and MEG/MRI alignment. hv_proc - Scripts for bids creation and QA of the datasets
Processing on Biowulf
To process the scripts on biowulf: pyctf & hv_proc must be in your conda path (if necessary add filepaths to a .pth file in the conda site-packages folder) module load ctf module load afni
Trigger Coding
Oddball Task
Description: 3 sound stimuli presented to the participant. The participant attends to the "standard" tone stimuli (210 epochs) and is required to respond to the "target" tone stimuli (45 epochs) that are intermixed with the standard tone. Additionally a broadband noise stimuli is presented as a "distractor" stimuli (45 epochs).
UADC003 - Left Ear auditory stimuli UADC004 - Right Ear auditory stimuli UADC005 - Participant response UPPT001 - Stimuli Coding (standard:1, target:2, distractor:3)
Hariri Hammer
Emotional processing task contrasting happy and sad faces. Shapes are used as neutral baselines. An initial "top stim" will be shown followed by a fixation crosshair. The subject is supposed to respond during the "choice stim" by pressing the left or right response button that corresponds to the face matching the "top stim" presentation.
UADC006 - Left response UADC007 - Right response UADC016 - Projector onset UPPT001 - Parallel port stimuli
Temporal Coding (UPPT001)
Top Stim Choice Stim Response Value
Stimulus Trigger codes (UPPT001)
diamond,0x1 moon,0x2 oval,0x3 plus,0x4 rectangle,0x5 trapezoid,0x6 triangle,0x7 hapmale,0xB hapfem,0xC sadmale,0x15 sadfem,0x16
Processing Scripts:
Files have been compiled into a folder hv_proc This contains script interfaces into the megblocks package